Expansion of antibody secreting cells and modulation of neutralizing antibody activity in HIV infected individuals undergoing structured treatment interruptions.

Although the differences did not reach statistical significance, the same tendency was observed for the levels of peripheral blood ASC, with the median frequency of the ASC being lower in on-treatment samples than in samples from off-treatment time points after the second and the third STI: 0.35% ASC [0.10-1.15] versus 0.25% [0.10-4.95] for the first STI, 0.35 [0.10-1.40] vs 0.85 [0.30-3.2] for the second STI and 0.30 [0.10-0.70] vs 0.40 [0.15-1.85], respectively for the third STI (Figure 2 b).

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