Barely Significant
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JAK2 V617F genotype is a strong determinant of blast transformation in primary myelofibrosis.

PLoS One · 2013 · PMC3608564 · PMID 23555782

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hedged sentence
0.0800
closest p · 1.6× alpha
0.0800
boldest claim

The sentences

did not reach statistical significanceP = 0.08so close (0.05 < p ≤ 0.1)
Finally, change in JAK2 V617F genotype during follow-up was associated with an increased risk of BT, which however did not reach statistical significance (HR 2.45, 95% CI, 0.89–6.71; P = 0.08) in a bivariable analysis including JAK2 V617F status at diagnosis.

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