Constitutive expression of Yes-associated protein (Yap) in adult skeletal muscle fibres induces muscle atrophy and myopathy.

Ctgf mRNA expression was significantly increased in transgenic mice following 5–7 weeks of doxycycline withdrawal compared to control mice ( Figure S3 ) and there was a trend for an increase in Col1A1 expression, but this did not reach statistical significance ( Figure S3 ).

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