Arginase activity - a marker of disease status in patients with visceral leishmaniasis in ethiopia.

PLoS Negl Trop Dis · 2013 · PMC3610885 · PMID 23556019

Europe PMC DOI

hedged sentences

0.0810

closest p · 1.6× alpha

0.3126

boldest claim

The sentences

a trend towards significancep = 0.081so close (0.05 < p ≤ 0.1)

We next assessed the expression levels of CD3ζ in CD4 + and CD8 + T cells in PBMCs: statistically significantly lower CD3ζ MFI in CD4 + T cells from patients before treatment (15.4±0.6) was observed as compared to controls (20.0±1.3, p = 0.0008); higher CD3ζ MFI in CD4 + T cells that shows a trend towards significance was observed in the treated patients (17.4±0.8, p = 0.081)( Figure 6B ).

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did not reach statistical significancep = 0.3126not close (p > 0.1)

Since arginase has been shown to be contained in the azurophilic granules found in the cytoplasm of neutrophils, we assessed its MFI in LDGs: the lower median values observed in the LDGs of VL patients did not reach statistical significance (controls: 24.9±1.7 vs VL patients: 19.4±1.4, p = 0.3126; VL patients: 19.4±1.4 vs treated patients: 23.4±1.0, p = 0.0855).

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