Impact of isoniazid preventive therapy on mortality among children less than 5 years old following exposure to tuberculosis at home in Guinea-Bissau: a prospective cohort study.

However, the excess mortality from 1996 to 1998 has changed to a marked trend of lower mortality in 2005–2008, which cannot solely be attributed to the drop in child mortality, and our data suggest that this is partly due to the introduction of IPT.

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There may be a slight trend towards better outcome in the contacts receiving IPT, although not significant.

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