The effects of increasing body mass index on heartburn severity, frequency and response to treatment with dexlansoprazole or lansoprazole.

With increasing baseline BMI, there was a significant trend toward increasing EO severity: LA Grades A/B and C/D were documented for 77.8% and 22.2%, respectively, of EO patients with BMI <25 kg/m 2 ; 70.8% and 29.2% of patients with BMI 25 to <30 kg/m 2 ; and 67.9% and 32.1% of patients with BMI ≥30 kg/m 2 ( P < 0.001).

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