Role of p73 in Alzheimer disease: lack of association in mouse models or in human cohorts.

Inspection of results within individual datasets revealed 28/540 (5.2%) of the comparisons were nominally significant (see Additional file 5 : Table S1) which is almost exactly the number of results expected to attain this level of significance due to chance alone.

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Previously the human TP73 gene was described as having borderline significant association with AD in a small dataset and that decreased p73 expression occurs in some cases of AD [ 23 ].

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