Genetic variations in SMAD7 are associated with colorectal cancer risk in the colon cancer family registry.

PLoS One · 2013 · PMC3616155 · PMID 23560096

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marginally significantno p-value reported

Marginally significant differences in the SNP-colorectal cancer associations were observed by use of nonsteroidal anti-inflammatory drugs, cigarette smoking, body mass index, and history of polyps.

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did not reach statistical significanceno p-value reported

We consistently observed a higher CRC OR for rs12953717 among individuals with ulcerative colitis than those without, although this difference did not reach statistical significance, possibly due to the small number of individuals with ulcerative colitis.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.