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SR-A and SREC-I are Kupffer and endothelial cell receptors for helper-dependent adenoviral vectors.

Mol Ther · 2013 · PMC3616528 · PMID 23358188

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Anti-SREC-I Fab also reduced HDAd uptake, even though the results did not reach statistical significance, while the combination of anti-SR-A and anti-SREC-I Fabs showed a statistically significant inhibitory effect on HDAd uptake (p<0.01 vs. unrelated Fab and p<0.05 vs.

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