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Procalcitonin-guided algorithm to reduce length of antibiotic therapy in patients with severe sepsis and septic shock.

BMC Infect Dis · 2013 · PMC3616901 · PMID 23547790

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Trends towards an average yearly reduction of 28-day mortality by −22.4% (95% CI −44.3 to 8.1; p=0.133) and mean cost for antibiotic therapy/ patient by −14.3 Euro (95% CI −55.7 to 27.1) did not reach statistical significance.

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