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Betaine supplement alleviates hepatic triglyceride accumulation of apolipoprotein E deficient mice via reducing methylation of peroxisomal proliferator-activated receptor alpha promoter.

Lipids Health Dis · 2013 · PMC3621752 · PMID 23497035

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showed a trendno p-value reported
The effect of betaine supplement on the expression of lipid metabolism related genes In the ApoE −/− mice, hepatic PPARα and CPT1 expression levels showed a trend of reduction when compared with WT mice, although the difference did not reach the statistical difference level.

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