Other studies showed no difference in CAG repeat length between patients with PCOS and controls, regardless of the fact that both alleles were considered together or separately [ 61 , 63 - 66 , 68 ][61,63-66,68]; however, when compared PCOS groups constructed by androgen levels, one of these studies showed a trend for lower CAG biallelic means in the subgroup of women with PCOS and lower testosterone levels, which was consistent with a role for androgen hyperactivity in the development of the syndrome [ 61 ].
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The role of androgen receptor activity mediated by the CAG repeat polymorphism in the pathogenesis of PCOS.
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