Cell counts using Trypan Blue staining showed that knockdown of Id1 decreased cell growth and induced cell death but did not reach statistical significance ( figure 7D,F ).
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Bone morphogenetic protein type I receptor antagonists decrease growth and induce cell death of lung cancer cell lines.
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Knockdown of Id3 did cause a highly significant decease in cell growth and induction of cell death when compared to controls ( figure 7D,F ).