The assays in Figs 7 and 8 display a clear trend where the disruption of sma causes a change in ampAOE phenotypes to WT, and a disruption of sma in WT cells mimics or phenocopies the ampA − phenotype.
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A SAP domain-containing protein shuttles between the nucleus and cell membranes and plays a role in adhesion and migration in D. discoideum.
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