FMR1, circadian genes and depression: suggestive associations or false discovery?

J Circadian Rhythms · 2013 · PMC3627611 · PMID 23521777

Europe PMC DOI

hedged sentences

0.0036

closest p · 0.1× alpha

0.0036

boldest claim

The sentences

nominally significantP=.0036actually significant

The gene-wise set test for the association of FMR1 with QIDS-SR was nominally significant with P=.0036, a probability which does not meet Bonferroni criteria for 36 genes tested (see Additional file 1 , sheet 2).

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highly significantno p-value reported

In the GAIN depression study [ 36 - 38 ], data were available only for rs25714 among the FMR1 SNPs that were highly significant in the Sleep Clinic study.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.