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Lysosomal basification and decreased autophagic flux in oxidatively stressed trabecular meshwork cells: implications for glaucoma pathogenesis.

Autophagy · 2013 · PMC3627672 · PMID 23360789

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closest p · 1.8× alpha
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boldest claim

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did not reach statistical significancep = 0.091so close (0.05 < p ≤ 0.1)
Also, although it did not reach statistical significance, LAMP1 and LAMP2A were found to be upregulated under chronic oxidative stress in all the cell lines tested ( LAMP1 : 1.849 ± 0.345 fold, p = 0.091, n = 4; LAMP2A : 1.987 ± 0.392 fold, p = 0.08, n = 4).

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