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Elevated t/e2 ratio is associated with an increased risk of cerebrovascular disease in elderly men.

PLoS One · 2013 · PMC3634802 · PMID 23637864

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a negative trendno p-value reported
Positive trends of FT and T/E 2 and a negative trend of FE 2 were detected, which were consistent with the values of exp(B) from logistic regression.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.