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Multivariate analysis of brain metabolism reveals chemotherapy effects on prefrontal cerebellar system when related to dorsal attention network.

EJNMMI Res · 2013 · PMC3637083 · PMID 23557152

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a marked trendno p-value reported
Both DAN and PCS are substrate of flexible, attention-based rapid processing skills that depend heavily on age and have a marked trend to decline with it [ 45 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.