Quality of life measures as a preliminary clinical indicator in patients with primary brain tumors.

The components of the HRQOL may represent independent predictors of survival and may be beneficial when used clinically to make treatment decisions.[ 7 ] Several studies in the literature on PBT have focused on the role of specific facets that may serve as significant prognostic factors of survival such as gender, cognitive and social functioning, depression, tumor location, and histological classification.[ 16 19 33 36 ] We have designed a study to attempt to determine which items of the EORTC QOL measures may be significant predictors of tumor progression on magnetic resonance imaging (MRI).

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The questions with significant or near-significant group differences over all questionnaire times are shown in Table 4 .

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