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Rapamycin attenuates the progression of tau pathology in P301S tau transgenic mice.

PLoS One · 2013 · PMC3646815 · PMID 23667480

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While a trend towards a reduction of tau tangles was noted in the hippocampus (p = 0.05), the lowering of the marked tangle pathology observed in the brain stem region did not reach statistical significance ( Fig. 2 ).

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