A case–control study including 501 breast cancer cases and 594 controls shows that green tea consumption has a significant trend of decreasing risk in a dose-dependent manner, after adjusting for potential confounding factors [ 13 ].
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EGCG, a major green tea catechin suppresses breast tumor angiogenesis and growth via inhibiting the activation of HIF-1α and NFκB, and VEGF expression.
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