Perforin is detrimental to controlling [corrected] C. muridarum replication in vitro, but not in vivo.

PLoS One · 2013 · PMC3653963 · PMID 23691028

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showed a trendno p-value reported

One study showed a trend toward less oviduct pathology in perforin knockout mice [15] , the other a statistically significant reduction [8] .

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.