Effects of CPAP on "vascular" risk factors in patients with obstructive sleep apnea and arterial hypertension.

Vasc Health Risk Manag · 2013 · PMC3656895 · PMID 23690688

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may be significantno p-value reported

29 It should be noted that this relatively minor central BP decrease may be significant in terms of prognosis, given the finding of the ASCOT-CAFÉ study that an intergroup difference of 3.6 mmHg in central BP decreased cardiovascular mortality by 24% and the risk of fatal and nonfatal stroke by 23%. 28 Moreover, the results of the CAFÉ study suggest that certain drugs have an “additional” effect on central BP, which may explain the benefits in terms of cardiovascular morbidity and mortality.

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did not reach statistical significanceno p-value reported

After antihypertensive treatment, any changes in AASI did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.