Peretinoin, an acyclic retinoid, improves the hepatic gene signature of chronic hepatitis C following curative therapy of hepatocellular carcinoma.

Moreover, Kaplan-Meier estimation of the survival ratio deduced from the same gene predictors showed a trend for improved survival of patients with non-recurrence expression patterns compared with those with the recurrence expression pattern ( P =0.12) (Figure 2 C, D).

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