Combination of selenium and green tea improves the efficacy of chemoprevention in a rat colorectal cancer model by modulating genetic and epigenetic biomarkers.

PLoS One · 2013 · PMC3662759 · PMID 23717604

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While the dose of 1ppm Se-enriched milk protein used in the present study was several fold greater than that used for human intervention studies (200 μg Se/day) [5] , our previous studies indicated that 1ppm Se was at the lowest range of Se forms to be effective in the AOM model, Se-enriched milk protein at 0.5ppm also showed a trend towards protection [28] .

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