Fatty acid synthase is a key target in multiple essential tumor functions of prostate cancer: uptake of radiolabeled acetate as a predictor of the targeted therapy outcome.

PLoS One · 2013 · PMC3669310 · PMID 23741342

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FASN expression showed a trend complementing that observed in the uptake of [1- 14 C]acetate ( Fig. 1A , lower): LNCaP cells showed higher FASN expression compared to the other cell lines ( P <0.01).

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