Corroborating our finding of an enrichment of genes that positively regulate among deletions, we also observe a highly significant enrichment of positive regulators among the more strongly-interconnected set of genes identified by Neale et al.
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Network topologies and convergent aetiologies arising from deletions and duplications observed in individuals with autism.
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Each of the 4 CNV set's candidate genes contribute to each of these enrichments with many sets nominally significant individually ( Table S7 ).