Among CLL patients with a mutated NOTCH1 gene 10/14 (71%) had an unmutated IGHV gene in contrast to 113/195 (58%) with a wildtype NOTCH1 gene, a difference that did not reach statistical significance (p = 0.22) (Figure 3 and Table 2 ).
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NOTCH1 mutations influence survival in chronic lymphocytic leukemia patients.
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