Effectiveness of a bundled intervention of decolonization and prophylaxis to decrease Gram positive surgical site infections after cardiac or orthopedic surgery: systematic review and meta-analysis.

BMJ · 2013 · PMC3681273 · PMID 23766464

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did not reach statistical significanceno p-value reported

Conversely, when the nine studies that compared glycopeptide prophylaxis alone with β lactam prophylaxis were combined, glycopeptide prophylaxis was a risk factor for Gram positive surgical site infections, though this result did not reach statistical significance (1.19, 0.99 to 1.45).

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