Prognostic significance of HIF-1α expression in hepatocellular carcinoma: a meta-analysis.

PLoS One · 2013 · PMC3683060 · PMID 23799043

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4 ), the heterogeneity was evident (χ 2 = 26.34, Ι 2 = 77.2%, P <0.001).Subgroup analysis showed a trend that elevated HIF-1α levels were associated with vascular invasion in HCC patients with preoperative adjuvant antitumor therapy [OR = 2.32 (95% CI:1.14, 4.74)].

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