Metabotropic glutamate receptor 5 positive allosteric modulators are neuroprotective in a mouse model of Huntington's disease.

Br J Pharmacol · 2013 · PMC3687670 · PMID 23489026

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did not reach statistical significanceno p-value reported

We have previously demonstrated that AKT activation by DHPG appeared more pronounced in neurons from a knock-in mouse model of HD than in control mice, although these difference did not reach statistical significance (Ribeiro et al ., 2010b ).

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