Barely Significant
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The ability of flux balance analysis to predict evolution of central metabolism scales with the initial distance to the optimum.

PLoS Comput Biol · 2013 · PMC3688462 · PMID 23818838

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a clear trendno p-value reported
Despite this, there was a clear trend.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.