Moderation of antipsychotic-induced weight gain by energy balance gene variants in the RUPP autism network risperidone studies.

Transl Psychiatry · 2013 · PMC3693401 · PMID 23799528

Europe PMC DOI

hedged sentences

0.0000

closest p · 0.0× alpha

0.0000

boldest claim

The sentences

highly significantP =1.3 × 10 −9actually significant

A model combining these three variants was highly significant ( P =1.3 × 10 −9 ) with a 0.85 effect size between lowest and highest risk groups.

also in 132,142 other papers

showed a trendno p-value reported

Several MC4R variants showed a trend association, but none met significance after correction for multiple comparisons (adjusted significance threshold for 19 markers P <0.003).

also in 53,322 other papers

did not achieve significanceno p-value reported

The single nonsynonymous variant in FAAH did not achieve significance in our data set.

also in 1,397 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.