Altered social behaviours in neurexin 1α knockout mice resemble core symptoms in neurodevelopmental disorders.

Male Nrxn1α KO mice showed a trend towards a decrease in the dark hour, but this did not reach significance.

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We observed an overall trend for a reduction in the time spent in more anxiogeneic areas of all three anxiety tasks, indicative of increased anxiety in Nrxn1α KO mice ( Figure 2 ).

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