Obesity, independent of p53 gene dosage, promotes mammary tumor progression and upregulates the p53 regulator microRNA-504.

PLoS One · 2013 · PMC3696069 · PMID 23840816

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did not reach statistical significanceP = 0.080so close (0.05 < p ≤ 0.1)

DIO, relative to control, also decreased E-cadherin and keratin 8 expression and increased total slug expression in Wnt-1 p53 +/+ tumor tissue, although the differences did not reach statistical significance (P = 0.080, P = 0.240 and P = 0.120, respectively).

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