A modest but significant effect of CGB5 gene promoter polymorphisms in modulating the risk of recurrent miscarriage.

Fertil Steril · 2013 · PMC3698440 · PMID 23499152

Europe PMC DOI

hedged sentences

0.1160

closest p · 2.3× alpha

0.1160

boldest claim

The sentences

did not reach statistical significanceP =.116not close (p > 0.1)

The meta-analysis including only Danish, Estonian, and Finnish female RM patients (n = 349) compared with fertile female controls (n = 314) showed the same direction and magnitude of the effect as the analysis in the full sample, but it did not reach statistical significance owing to the smaller sample size (c5-155: P =.116; OR = 0.71; 95% CI, 0.46–1.08; c5-142: P =.089; OR = 0.68; 95% CI, 0.44–1.06).

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a nonsignificant trendno p-value reported

In Danes, two CGB5 promoter SNPs (c5-155; c5-142) exhibited a nonsignificant trend for higher allele frequency in fertile women compared with RM patients.

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