The impact of Bdnf gene deficiency to the memory impairment and brain pathology of APPswe/PS1dE9 mouse model of Alzheimer's disease.

PLoS One · 2013 · PMC3700921 · PMID 23844236

Europe PMC DOI

hedged sentences

0.0500

closest p · 1.0× alpha

0.0700

boldest claim

The sentences

marginally significantp = 0.05actually significant

The APdE9 x Bdnf interaction remained marginally significant in females (p = 0.05), but did not reach significance in males (p = 0.08).

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showed a trendp = 0.07so close (0.05 < p ≤ 0.1)

Both male and female Bdnf +/− showed a trend toward increased path length (p = 0.07, for both genders).

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of borderline significanceno p-value reported

However, in cases of borderline significance, we also assessed the effects with males and females combined.

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highly significantno p-value reported

These findings together with a highly significant increase in thigmotaxis among Bdnf +/− male mice strongly suggest that Bdnf +/− mice were impaired in the Morris swim task acquisition independent of obesity and decreased swimming speed associated with the Bdnf +/− genotype.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.