Similar differences were observed in the current study, however percent activity during the light phase did not reach statistical significance (figure not shown) after correction for multiple comparisons between the MPS IIIB NO TX (mean = 15.14%) and the Normal NO TX group (mean = 9.60%)(p = 0.14).
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Disease correction by combined neonatal intracranial AAV and systemic lentiviral gene therapy in Sanfilippo Syndrome type B mice.
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