HES1, a target of Notch signaling, is elevated in canine osteosarcoma, but reduced in the most aggressive tumors.

BMC Vet Res · 2013 · PMC3701487 · PMID 23816051

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did not reach statistical significanceno p-value reported

Consistent with our RT-qPCR results, average HES1 immunohistochemical staining was lower in tumors from dogs with DFI < 100 days, but because of low power did not reach statistical significance (Additional file 6 ).

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