An apolipoprotein A-I mimetic peptide designed with a reductionist approach stimulates reverse cholesterol transport and reduces atherosclerosis in mice.

There was a slight reduction in percent of area occupied by plaques in the whole aorta in the ELK-2A2K2E group compared to the vehicle group at both time points after en face analysis, however the difference did not reach statistical significance ( Fig. 2A ).

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