The prognostic value of tumor necrosis in patients undergoing stereotactic radiosurgery of brain metastases.

Radiat Oncol · 2013 · PMC3707781 · PMID 23822663

Europe PMC DOI

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closest p · 1.0× alpha

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boldest claim

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marginal significancep = 0.05actually significant

Significant prognostic factors for overall survival were KPS (p = 0.001), presence of tumor necrosis on pretreatment MRI (p = 0.001) with RPA-class and WBI reaching marginal significance (each p = 0.05).

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of marginal significancep = 0.05actually significant

The Karnofsky performance status (p = 0.001) and the presence of tumor necrosis on pretreatment MRI (p = 0.001) were the most important prognostic factors in the multivariate analysis with the RPA-class and WBI as additional prognostic factors of marginal significance (p = 0.05).

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