Evaluation of excess significance bias in animal studies of neurological diseases.

PLoS Biol · 2013 · PMC3712913 · PMID 23874156

Europe PMC DOI

hedged sentence

0.0000

closest p · 0.0× alpha

0.0000

boldest claim

The sentences

nominally significantp <10 −9actually significant

Assuming the effect size in the most precise study to be a plausible effect, 919 out of 4,445 nominally significant results were expected versus 1,719 observed ( p <10 −9 ).

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