N-acetylcysteine and allopurinol confer synergy in attenuating myocardial ischemia injury via restoring HIF-1α/HO-1 signaling in diabetic rats.

PLoS One · 2013 · PMC3715528 · PMID 23874823

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did not reach statistical significanceno p-value reported

Values for mean arterial blood pressure (MAP, a major hemodynamic parameter) and the product of heart rate and MAP (RPP) were relatively lower in diabetic rats compared to control rats at baseline (i.e., before inducing ischemia), but these difference did not reach statistical significance ( Fig. 2 C & E).

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