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Validation of microarray data in human lymphoblasts shows a role of the ubiquitin-proteasome system and NF-kB in the pathogenesis of Down syndrome.

BMC Med Genomics · 2013 · PMC3717290 · PMID 23830204

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showed a trendno p-value reported
DS cells showed a trend to increase ubiquitin-bound proteins after OS induction.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.