3 B , left panel) showed that whole pancreatic glucagon protein content was lower in the diabetic SSTR2a group (11.94 ± 0.67 ng/mg protein) compared with the diabetic vehicle group (18.28 ± 1.36 ng/mg protein; P < 0.001), and tended to be lower compared with the nondiabetic groups, although these differences failed to reach statistical significance after adjusting for multiple comparisons.
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Somatostatin receptor type 2 antagonism improves glucagon counterregulation in biobreeding diabetic rats.
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