In type 1 diabetic patients ( n = 21), a positive correlation was observed between total gray matter CBF and CMR glu ( R = 0.5; P < 0.05), whereas this correlation did not reach statistical significance in healthy volunteers ( n = 8; R = 0.6; P = 0.1).
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Cerebral blood flow and glucose metabolism measured with positron emission tomography are decreased in human type 1 diabetes.
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