Tumor site- and stage-specific associations between allelic variants of glutathione S-transferase and DNA-repair genes and overall survival in colorectal cancer patients receiving 5-fluorouracil-based chemotherapy.

PLoS One · 2013 · PMC3720885 · PMID 23894404

Europe PMC DOI

hedged sentence

0.0510

closest p · 1.0× alpha

0.0510

boldest claim

The sentences

approached significanceP = 0.051so close (0.05 < p ≤ 0.1)

The association between the XRCC1 Gln allelic variants and reduced OS in stage II/III patients approached significance (HR = 1.41, 95% CI = 1.00–1.99, P = 0.051, FDR = 0.510).

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