A specific expression profile of heat-shock proteins and glucose-regulated proteins is associated with response to neoadjuvant chemotherapy in oesophageal adenocarcinomas.

Analysing subgroups of patients according to the CTX regime applied, significant association between HSP/GRP expression pattern and down-categorisation after CTX hold true for the PLF/OLF-treated patients ( P =0.035); however, regarding the small subgroup of patients who additionally were treated with Paclitaxel (T-PLF/OLF), there was only a trend similar between GSP/GRP patterns and response/down-categorisation, which did not reach statistical significance (see Supplementary file 2 ).

also in 111,027 other papers