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Usp18 deficient mammary epithelial cells create an antitumour environment driven by hypersensitivity to IFN-λ and elevated secretion of Cxcl10.

EMBO Mol Med · 2013 · PMC3721472 · PMID 23681607

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There was also a trend to an elevated number of CD8 + T cells, natural killer (NK1.1) cells and F4/80 + macrophages in PyVmT/Usp18 KO tumours though the difference did not reach statistical significance.

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