The synergistic necrohemorrhagic action of Clostridium perfringens perfringolysin and alpha toxin in the bovine intestine and against bovine endothelial cells.

The plc -complemented Δ pfoA Δ plc mutant (or pfoA -deficient strain) could induce necrotic lesions in fewer loops as compared to the wild-type strain, but the difference in number of necrotic loops did not reach statistical significance.

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